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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf25
All Species:
26.67
Human Site:
Y148
Identified Species:
65.19
UniProt:
Q8IW50
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW50
NP_671735.1
185
20400
Y148
I
Q
L
L
K
D
G
Y
R
L
D
E
I
P
D
Chimpanzee
Pan troglodytes
XP_001161024
185
20399
Y148
I
Q
L
L
K
D
G
Y
R
L
D
E
I
P
D
Rhesus Macaque
Macaca mulatta
XP_001088997
270
28968
Y233
I
Q
L
L
K
D
G
Y
R
L
D
E
I
P
D
Dog
Lupus familis
XP_531979
185
20381
Y148
I
Q
L
L
K
D
G
Y
R
L
D
E
I
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D772
157
17474
E124
K
D
G
Y
R
L
D
E
I
P
D
D
E
D
L
Rat
Rattus norvegicus
NP_001103086
157
17476
E124
K
D
G
Y
R
L
D
E
I
P
D
D
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511942
230
24741
Y191
R
Q
L
L
Q
D
G
Y
H
L
D
E
I
P
D
Chicken
Gallus gallus
XP_001231783
185
20582
Y148
I
Q
L
L
K
D
G
Y
R
L
D
E
I
P
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DC60
186
20685
Y149
I
Q
L
L
K
D
G
Y
R
L
D
E
I
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178400
193
22137
F158
Q
Q
L
L
K
D
G
F
R
L
D
E
V
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
68.1
100
N.A.
83.7
83.7
N.A.
36.5
95.1
N.A.
87
N.A.
N.A.
N.A.
N.A.
39.3
Protein Similarity:
100
100
68.1
100
N.A.
84.3
83.7
N.A.
50
96.7
N.A.
91.9
N.A.
N.A.
N.A.
N.A.
55.4
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
80
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
86.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
80
20
0
0
0
100
20
0
20
80
% D
% Glu:
0
0
0
0
0
0
0
20
0
0
0
80
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
0
0
0
80
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
60
0
0
0
0
0
0
0
20
0
0
0
70
0
0
% I
% Lys:
20
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
80
80
0
20
0
0
0
80
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
20
0
0
0
80
0
% P
% Gln:
10
80
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
20
0
0
0
70
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _